Endothelial Glycocalyx Support
The Part Of Your Artery Nobody Told You About
Every blood vessel in your body is lined with a micro-thin, slippery gel layer called the endothelial glycocalyx. It is the buffer between your blood and your artery wall, and it is fragile. Arterosil HP with MonitumRS is the gold standard for supporting it. Sixty vegan capsules, a one-month supply at recommended dosing.
Researchers first imaged this layer directly in living capillaries and found it far thicker than anyone expected, occupying a substantial share of the vessel channel itself. Original illustration; structure as characterized in van den Berg, Vink and Spaan, Circulation Research 2003;92:592-594.
Why The Glycocalyx Matters
For decades, cardiology looked at the artery wall and the blood flowing through it and largely ignored what sat in between. That thin gel layer turns out to be one of the most actively researched structures in human health, and it does far more than line the vessel. It supports the health of the endothelium underneath. It harbors antioxidants and coagulation factors. It regulates which molecules pass through to the endothelium. It participates in triggering nitric oxide production and the vasodilation that follows.
The glycocalyx is also delicate. Poor diet, oxidative stress, high blood sugar, inadequate sleep, chronic stress and aging all wear on it. That is the root-cause conversation. The number on your lab slip is downstream. The condition of this layer is upstream, and it is something you can actively support.
Illustration for education. Layer proportions are exaggerated for clarity; the glycocalyx is measured in microns.
What Makes Arterosil HP Different
Arterosil HP uniquely contains MonitumRS, a proprietary full-spectrum extract of rhamnan sulfate, a specialized sulfated polysaccharide from the rare green seaweed Monostroma nitidum, sustainably harvested in the traditional manner by local fishermen in the Pacific. Rhamnan sulfate is what researchers classify as a glycocalyx-regenerating compound. MonitumRS is scientifically shown to protect and restore the endothelial glycocalyx.†
MonitumRS is then enhanced with a blend of fruit, vegetable and green tea extracts chosen for their antioxidant properties, which support the effects of MonitumRS by reducing oxidative stress. This is a formula built around one well-studied primary compound with supporting nutrients, not a long ingredient list assembled for label appeal.
Illustration for education. Not a depiction of results from any individual using this product.
What It Supports
Supports a strong and vital glycocalyx, the micro-thin gel lining of your veins and arteries*
Supports normal circulation*
Helps support normal artery function*
Helps maintain a healthy artery wall*
Supports a healthy heart*
Supports antioxidant defenses against oxidative stress*
Why Dr. Wolfson Uses It
Root cause cardiology asks a different question than the one most patients get asked. Not what is your number, but what is happening to the tissue. When someone comes to us with arterial plaque, blood pressure that will not settle, circulation complaints, or testing that points toward endothelial trouble, the health of the vessel lining is one of the first things on the list. Arterosil HP is the product we reach for to support that structure directly, and it anchors our Coronary Artery Disease Bundle for exactly that reason.
It is not a replacement for real food, sunshine, sleep, movement, and testing. Those come first. This is the sixth pillar of the 100 Year Heart Method doing focused work in the background while the foundation gets built.
The Research Behind The Ingredient
Rhamnan sulfate from Monostroma nitidum has been the subject of roughly thirty years of scientific investigation, primarily in cardiovascular health, with more than fifty papers on PubMed referencing it and independent studies conducted at major research institutions. Arterosil HP also has published human research on its full formula, which is uncommon in this category, where most products rest on ingredient studies alone.
Read the research honestly: the human work published to date is early-stage rather than large randomized trial evidence, and mechanism is not the same thing as outcome. We would rather tell you that plainly than oversell it.
Quality And Sourcing
Vegan and non-GMO. Manufactured in the United States under a total quality system with strict compliance to current good manufacturing practices as defined by the FDA, with batch and test records maintained throughout production. Arterosil is a registered trademark of Calroy Health Sciences. U.S. Patent No. 11,135,238, international patents pending.
Supplement Facts

How To Use
One capsule twice per day with food, morning and evening, or as directed by your practitioner. Sixty capsules is a one-month supply at that dosing.
Take it consistently. Supporting the glycocalyx is a slow build rather than an overnight switch, and most people should plan on a minimum of three months before evaluating, ideally alongside repeat testing rather than by feel alone.
Cautions
If you are pregnant, nursing, or taking prescription medication, consult your physician before use. If you take a blood thinner or antiplatelet medication, or have a procedure or dental work scheduled, review this with your prescribing physician or pharmacist first.
† As demonstrated in an independent third-party laboratory in vitro study.
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
The information on this page is educational and is not a substitute for individualized medical advice. Consult your physician before beginning any supplement.

